MemBrain: Transmembrane protein structure prediction

MemBrain: Transmembrane protein structure prediction

Input protein sequence below (Example):

Prediction function:

α-TMP Topology prediction using deep learning
Transmembrane helix¹ Amphipathic helix²
3D structure model prediction
I have no residue-residue contact restraint
I have residue-residue contact restraint(?)

TMH-TMH residue contact prediction
TMH prediction
Rasa prediction

N-terminal signal peptide prediction

I know there is NO N-terminal signal peptide (?)

I do NOT know whether there is signal peptide in the N-terminal or not (?)

Human	Plant	Animal
Other-Eukaryotic	Gram-positive	Gram-negative

Email address:

     You may also be interested in the following servers:
     (1) Cyscon (Disulfide connectivity pattern prediction)
     (2) R₂C (Residue contact map prediction)
     (3) Signal-3L (Signal peptide prediction)

¹ Feng, Shi-Hao, et al. Topology prediction improvement of α-helical transmembrane proteins through helix-tail modeling and multiscale deep learning fusion. Journal of molecular biology 432.4 (2020): 1279-1296.
² Feng, Shi-Hao, et al. Ab-initio Membrane Protein Amphipathic Helix Structure Prediction Using Deep Neural Networks. IEEE/ACM Transactions on Computational Biology and Bioinformatics (2020).

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