Viruses can reproduce their progenies only within a host cell, and their actions
depend both on its destructive tendencies toward a specific host cell and on environmental
conditions. Therefore, knowledge of the subcellular localization of viral proteins in a
host cell or virus-infected cell is very useful for in-depth studying their functions and
mechanisms as well as designing antiviral drugs. Virus-PLoc has been developed for prediction of the subcellular localization of viral proteins within host and virus-infected cells. |
Caveat |
Application scope: The predictor is for virus protein samples only that covers the following 7 subcellular locations: (1) cytoplasm, (2) endoplasmic reticulum, (3) extracell, (4) inner capsid, (5) nucleus, (6) outer capsid, and (7) plasma membrane. Stop prediction if the query protein is known not a virus protein or not one of the above 7 locations, because the result obtained might not make any sense. |