Table. The hydrophobicity, hydrophilicity, mass,pK1(alpha-COOH), pK2(NH3) and pI(at 25oC) values used by PseAA
| Amino acid | Hydrophobicity a | Hydrophilicity b | Mass c | pK1(a-CO2H) d | pK2(NH3) d | pI(at 25oC) d |
| A | 0.62 | -0.5 | 15.0 | 2.35 | 9.87 | 6.11 |
| C | 0.29 | -1.0 | 47.0 | 1.71 | 10.78 | 5.02 |
| D | -0.90 | 3.0 | 59.0 | 1.88 | 9.60 | 2.98 |
| E | -0.74 | 3.0 | 73.0 | 2.19 | 9.67 | 3.08 |
| F | 1.19 | -2.5 | 91.0 | 2.58 | 9.24 | 5.91 |
| G | 0.48 | 0.0 | 1.0 | 2.34 | 9.60 | 6.06 |
| H | -0.40 | -0.5 | 82.0 | 1.78 | 8.97 | 7.64 |
| I | 1.38 | -1.8 | 57.0 | 2.32 | 9.76 | 6.04 |
| K | -1.50 | 3.0 | 73.0 | 2.20 | 8.90 | 9.47 |
| L | 1.06 | -1.8 | 57.0 | 2.36 | 9.60 | 6.04 |
| M | 0.64 | -1.3 | 75.0 | 2.28 | 9.21 | 5.74 |
| N | -0.78 | 0.2 | 58.0 | 2.18 | 9.09 | 10.76 |
| P | 0.12 | 0.0 | 42.0 | 1.99 | 10.60 | 6.30 |
| Q | -0.85 | 0.2 | 72.0 | 2.17 | 9.13 | 5.65 |
| R | -2.53 | 3.0 | 101.0 | 2.18 | 9.09 | 10.76 |
| S | -0.18 | 0.3 | 31.0 | 2.21 | 9.15 | 5.68 |
| T | -0.05 | -0.4 | 45.0 | 2.15 | 9.12 | 5.60 |
| V | 1.08 | -1.5 | 43.0 | 2.29 | 9.74 | 6.02 |
| W | 0.81 | -3.4 | 130.0 | 2.38 | 9.39 | 5.88 |
| Y | 0.26 | -2.3 | 107.0 | 2.20 | 9.11 | 5.63 |
| a The hydrophobicity values are from JACS, 1962, 84: 4240-4246. (C. Tanford). |
| b The hydrophilicity values are from PNAS, 1981, 78:3824-3828 (T.P.Hopp & K.R.Woods). |
| c The side-chain mass for each of the 20 amino acids. |
d CRC Handbook of Chemistry and Physics, 66th ed., CRC Press, Boca Raton, Florida
(1985).
R.M.C. Dawson, D.C. Elliott, W.H. Elliott, K.M. Jones, Data for Biochemical Research
3rd ed., Clarendon Press Oxford (1986). |
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