NLS segment recommended by NLSExplorer

Position Prediction type NLS indicates Nuclear Localization Signals, NIA means potential Nuclear Important Area in protein sequence. Length Recommendation score Entropy score Rcommended NLS segment
130-136 NLS 70.994912.23593TGTKRKL
149-161 NLS 130.994482.80739QFNKIKLRPKYKK



Segment Similarity Information

Each NLS we show similarity in top-5 of predicted NLS from NLS candidate library
NLS Similar NLS Uni ID Species Probability Position
TGTKRKL IKKRKA P38937 Schizosaccharomyces pombe 0.9934622049331665 8-13
SVKRKS Q9XIF2 Arabidopsis thaliana 0.9944832921028137 2-7
MTKKRKLE Q9LES2 Arabidopsis thaliana 0.9962660670280457 0-7
VKKRKL Q02206 Saccharomyces cerevisiae 0.9959314465522766 2-7
TSVKRKASE P53254_1 Saccharomyces cerevisiae 0.9940599799156189 2-10
QFNKIKLRPKYKK PPVRAEKKRKT O74560 Schizosaccharomyces pombe 0.9950234889984131 1-11
IMSDSKKIKVD P19659_2 Saccharomyces cerevisiae 0.9943709969520569 0-10
GCIRKRWLRKPRPVSL Q12789_3 Homo sapiens 0.9949774146080017 0-15
KRKRVE O94328 Schizosaccharomyces pombe 0.9950109720230103 3-8
LRKKIKSF P06777_2 Saccharomyces cerevisiae 0.9935251474380493 2-9



Potential segment important for nuclear transport

Position Prediction type NLS indicates Nuclear Localization Signals, NIA means potential Nuclear Important Area in protein sequence. Length Recommendation score Entropy score Rcommended NLS segment
454-459 NIA 60.361661.25163LKKVKK
518-528 NIA 110.017553.0958VIQKYNRFKHH
563-579 NIA 170.007343.38158DAITFAEQKLNCKYKKF
419-424 NIA 60.007232.25163NKKSTL
548-553 NIA 60.005881.25163LKLLAL
534-539 NIA 60.005822.25163KVNRRE
368-373 NIA 60.004832.25163LSRKES
202-207 NIA 60.00422.25163MRFDDN
260-265 NIA 60.003831.79248NRVFVV
268-273 NIA 60.003812.58496DKIRFM
490-495 NIA 60.003722.25163NEERLT
311-316 NIA 60.003542.25163HHTFKA
300-305 NIA 60.003251.9183QNCKKC
340-345 NIA 60.003182.58496LGERKC
32-37 NIA 60.00282.58496QPNDYL
18-23 NIA 60.002372.58496RASFDN
54-59 NIA 60.00212.25163DSETAA
65-70 NIA 60.002072.25163ASVNSL



Attention distribution along the sequence





Sequence visualization according to the attention map





The structure statistical of recommended segment





The recommended segment visualization on 3d structure

The green, blue, and yellow regions refer to the top three recommended NLS,
while the red region represents other potential NLS regions