On Optimizing Gaussian Function based Similarity Metric in Computational Biology

 

Gaussian kernel is a popular kernel function often used in various computational biology and their applications to measure the similarity between two samples in a dataset. It can be used not only in the unsupervised situation but also in the supervised case. However, the scalar parameter belta (¦Â) in Gaussian kernel function as shown in the following equation significantly affects the final results. This online data-driven tool is used to calculate the optimal belta (¦Â) parameter based on the given dataset.

Note:
(1)
When using this online service, the user is required to submit their dataset with a file named *.txt, for example "in.txt" .
(2) For very large-size or very high-dimensional datasets, the users need to download the stand alone program.

 

For Supervised Case:

Please upload your dataset (Example): 



 

 

For Unsupervised Case:

Please upload your dataset (Example):



 
 
References:

Jian-Bo Lei, Jiang-Bo Yin, and Hong-Bin Shen, GFO: A data driven approach for optimizing Gaussian function based similarity metric in computational biology, Neurocomputing, 2013, 99: 307-315.

Jiang-Bo Yin, Tao Li, and Hong-Bin Shen, Gaussian kernel optimization: complex problem and a simple solution, Neurocomputing, 2011, 74: 3816-3822.

 
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